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Biased reading frames of pre-existing DH--JH coding joints and preferential nucleotide insertions at VH--DJH signal joints of excision products of immunoglobulin heavy chain gene rearrangements.

During B cell differentiation immunoglobulin (Ig) DH segments join to JH segments, followed by joining of VH to DJH. Although circular excision products of DH--JH rearrangements have been characterized, excision products of VH to DJH joining have never been isolated. We selectively denatured chromos...

Полное описание

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Библиографические подробности
Главные авторы: Shimizu, T, Yamagishi, H
Формат: Artigo
Язык:Inglês
Опубликовано: 1992
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC556964/
https://ncbi.nlm.nih.gov/pubmed/1464314
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