Enhancing antitumor immunogenicity of HPV16-E7 DNA vaccine by fusing DNA encoding E7-antigenic peptide to DNA encoding capsid protein L1 of Bovine papillomavirus

BACKGROUND: Human papillomavirus (HPV) has been identified as the primary etiologic factor of cervical cancer, the fourth leading cause of cancer death in females worldwide. We have previously shown that coadministration of DNA encoding L1 capsid protein of Bovine papillomavirus (BPV) can enhance th...

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Veröffentlicht in:Cell Biosci
Hauptverfasser: Yang, Andrew, Peng, Shiwen, Farmer, Emily, Zeng, Qi, Cheng, Max A., Pang, Xiaowu, Wu, T. -C., Hung, Chien-Fu
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2017
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Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5569540/
https://ncbi.nlm.nih.gov/pubmed/28852471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13578-017-0171-5
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