uPA‐derived peptide, Å6 is involved in the suppression of lipopolysaccaride‐promoted inflammatory osteoclastogenesis and the resultant bone loss

INTRODUCTION: Chronic inflammatory diseases such as rheumatoid arthritis and periodontitis frequently cause bone destruction. Inflammation‐induced bone loss results from the increase of bone‐resorbing osteoclasts. Recently, we demonstrated that urokinase type plasminogen activator (uPA) suppressed l...

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Veröffentlicht in:Immun Inflamm Dis
Hauptverfasser: Kanno, Yosuke, Maruyama, Chihiro, Matsuda, Ayaka, Ishisaki, Akira
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2017
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Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5569370/
https://ncbi.nlm.nih.gov/pubmed/28493442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/iid3.169
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