uPA‐derived peptide, Å6 is involved in the suppression of lipopolysaccaride‐promoted inflammatory osteoclastogenesis and the resultant bone loss

INTRODUCTION: Chronic inflammatory diseases such as rheumatoid arthritis and periodontitis frequently cause bone destruction. Inflammation‐induced bone loss results from the increase of bone‐resorbing osteoclasts. Recently, we demonstrated that urokinase type plasminogen activator (uPA) suppressed l...

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Bibliographic Details
Published in:Immun Inflamm Dis
Main Authors: Kanno, Yosuke, Maruyama, Chihiro, Matsuda, Ayaka, Ishisaki, Akira
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2017
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Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5569370/
https://ncbi.nlm.nih.gov/pubmed/28493442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/iid3.169
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