Phorbol ester impairs electrical excitation of rat pancreatic beta-cells through PKC-independent activation of K(ATP) channels

BACKGROUND: Phorbol 12-myristate 13-acetate (PMA) is often used as an activating phorbol ester of protein kinase C (PKC) to investigate the roles of the kinase in cellular functions. Accumulating lines of evidence indicate that in addition to activating PKC, PMA also produces some regulatory effects...

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Autors principals: Suga, Sechiko, Wu, Jie, Ogawa, Yoshiji, Takeo, Teruko, Kanno, Takahiro, Wakui, Makoto
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2001
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC55693/
https://ncbi.nlm.nih.gov/pubmed/11560763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2210-1-3
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