The scaffold protein Ajuba suppresses CdGAP activity in epithelia to maintain stable cell-cell contacts

Levels of active Rac1 at epithelial junctions are partially modulated via interaction with Ajuba, an actin binding and scaffolding protein. Here we demonstrate that Ajuba interacts with the Cdc42 GTPase activating protein CdGAP, a GAP for Rac1 and Cdc42, at cell-cell contacts. CdGAP recruitment to j...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Sci Rep
Autors principals: McCormack, J. J., Bruche, S., Ouadda, A. B. D., Ishii, H., Lu, H., Garcia-Cattaneo, A., Chávez-Olórtegui, C., Lamarche-Vane, N., Braga, V. M. M.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2017
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5569031/
https://ncbi.nlm.nih.gov/pubmed/28835688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-09024-4
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars