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Generation of Nkx2-5/CreER Transgenic Mice for Inducible Cre Expression in Developing Hearts

Nkx2-5 is a homeobox-containing transcriptional regulator that serves as one of the earliest markers of cardiac lineage commitment. To study the role of Nkx2-5-expressing progenitors at specific time points in cardiac development, we have generated a novel and inducible NKX2-5 mouse line by knocking...

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Bibliographische Detailangaben
Veröffentlicht in:Genesis
Hauptverfasser: Ranjbarvaziri, Sara, Park, Shuin, Nguyen, Ngoc B., Gilmore, William B., Zhao, Peng, Ardehali, Reza
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5568924/
https://ncbi.nlm.nih.gov/pubmed/28589709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dvg.23041
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