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Retinol-Binding Site in Interphotoreceptor Retinoid-Binding Protein (IRBP): A Novel Hydrophobic Cavity

PURPOSE: Interphotoreceptor retinoid-binding protein (IRBP) appears to target and protect retinoids during the visual cycle. X-ray crystallographic studies had noted a ββα-spiral fold shared with crotonases and C-terminal protein transferases. The shallow cleft formed by the fold was assumed to repr...

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Detalhes bibliográficos
Publicado no:Invest Ophthalmol Vis Sci
Main Authors: Gonzalez-Fernandez, Federico, Bevilacqua, Thomas, Lee, Kee-Il, Chandrashekar, Reena, Hsu, Larson, Garlipp, Mary Alice, Griswold, Jennifer B., Crouch, Rosalie K., Ghosh, Debashis
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5568800/
https://ncbi.nlm.nih.gov/pubmed/19608538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.08-1857
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