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Phosphorylation of CREB affects its binding to high and low affinity sites: implications for cAMP induced gene transcription.

Cyclic AMP treatment of hepatoma cells leads to increased protein binding at the cyclic AMP response element (CRE) of the tyrosine aminotransferase (TAT) gene in vivo, as revealed by genomic footprinting, whereas no increase is observed at the CRE of the phosphoenolpyruvate carboxykinase (PEPCK) gen...

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Foilsithe in:EMBO J
Main Authors: Nichols, M, Weih, F, Schmid, W, DeVack, C, Kowenz-Leutz, E, Luckow, B, Boshart, M, Schütz, G
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group 1992
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC556868/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1354612/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1992.tb05412.x
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