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Metabolic control of the scaffold protein TKS5 in tissue-invasive, pro-inflammatory T cells
Pathogenic T cells in rheumatoid arthritis (RA) infiltrate non-lymphoid tissue sites, maneuver through extra-cellular matrix and form lasting inflammatory microstructures. Here, we found that RA T cells abundantly express the podosome scaffolding protein TKS5, enabling them to form tissue-invasive m...
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| Publicado no: | Nat Immunol |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5568495/ https://ncbi.nlm.nih.gov/pubmed/28737753 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.3808 |
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