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SSB recruitment of Exonuclease I aborts template-switching in Escherichia coli

Misalignment of a nascent strand and the use of an alternative template during DNA replication, a process termed “template-switching”, can give rise to frequent mutations and genetic rearrangements. Mutational hotspots are frequently found associated with imperfect inverted repeats (“quasipalindrome...

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Publicat a:DNA Repair (Amst)
Autors principals: Laranjo, Laura T., Gross, Stephen J., Zeiger, Danna M., Lovett, Susan T.
Format: Artigo
Idioma:Inglês
Publicat: 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5568474/
https://ncbi.nlm.nih.gov/pubmed/28605670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2017.05.007
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