Nuclear envelope-distributed CD147 interacts with and inhibits the transcriptional function of RING1 and promotes melanoma cell motility

Melanoma accounts for nearly 80% of all deaths associated with skin cancer.CD147 plays a very important role in melanoma progression and the expression level may correlate with tumor malignancy. RING1 can bind DNA and act as a transcriptional repressor, play an important role in the aggressive pheno...

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Publicat a:PLoS One
Autors principals: Chen, Junchen, Peng, Cong, Lei, Li, Zhang, Jianglin, Zeng, Weiqi, Chen, Xiang
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2017
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5568409/
https://ncbi.nlm.nih.gov/pubmed/28832687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0183689
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