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VCP, the mammalian homolog of cdc48, is tyrosine phosphorylated in response to T cell antigen receptor activation.

Activation of T cells through the T cell antigen receptor (TCR) results in the rapid tyrosine phosphorylation of a number of cellular proteins, one of the earliest being a 100 kDa protein. We have sought to identify this 100 kDa substrate by partially purifying the protein by antiphosphotyrosine (AP...

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Détails bibliographiques
Auteurs principaux: Egerton, M, Ashe, O R, Chen, D, Druker, B J, Burgess, W H, Samelson, L E
Format: Artigo
Langue:Inglês
Publié: 1992
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC556811/
https://ncbi.nlm.nih.gov/pubmed/1382975
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