A chimeric ubiquitin conjugating enzyme that combines the cell cycle properties of CDC34 (UBC3) and the DNA repair properties of RAD6 (UBC2): implications for the structure, function and evolution of the E2s.

The CDC34 (UBC3) protein from Saccharomyces cerevisiae has a 125 residue tail that contains a polyacidic region flanked on either side by sequences of mixed composition. We show that although a catalytic domain is essential for CDC34 activity, a major cell cycle determinant of this enzyme is found w...

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Veröffentlicht in:	EMBO J
Hauptverfasser:	Silver, E T, Gwozd, T J, Ptak, C, Goebl, M, Ellison, M J
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Nature Publishing Group 1992
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC556793/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1639076/ https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1992.tb05381.x
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