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Cross-seeding of prions by aggregated α-synuclein leads to transmissible spongiform encephalopathy

Aggregation of misfolded proteins or peptides is a common feature of neurodegenerative diseases including Alzheimer’s, Parkinson’s, Huntington’s, prion and other diseases. Recent years have witnessed a growing number of reports of overlap in neuropathological features that were once thought to be un...

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Publicat a:PLoS Pathog
Autors principals: Katorcha, Elizaveta, Makarava, Natallia, Lee, Young Jin, Lindberg, Iris, Monteiro, Mervyn J., Kovacs, Gabor G., Baskakov, Ilia V.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5567908/
https://ncbi.nlm.nih.gov/pubmed/28797122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006563
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