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Cardiomyocyte Ca(2+) homeostasis as a therapeutic target in heart failure with reduced and preserved ejection fraction

Heart failure is a highly prevalent syndrome of multiple etiologies and associated comorbidities, and aberrant intracellular Ca(2+) homeostasis is a hallmark finding in heart failure patients. The cyclical changes in Ca(2+) concentration within cardiomyocytes control cycles of cardiac contraction an...

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Bibliographische Detailangaben
Veröffentlicht in:Curr Opin Pharmacol
Hauptverfasser: Peana, Deborah, Domeier, Timothy L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5567788/
https://ncbi.nlm.nih.gov/pubmed/28437711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coph.2017.03.005
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