IL-21/anti-Tim1/CD40 ligand promotes B10 activity in vitro and alleviates bone loss in experimental periodontitis in vivo

IL-10-expressing regulatory B cells (B10) play an essential role in immune system balance by suppressing excessive inflammatory responses. In this study, we investigated induction of B 10 cell’s IL-10 competency in vitro and its effect on ligature-induced experimental periodontitis in vivo. Spleen B...

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Bibliografiske detaljer
Udgivet i:Biochim Biophys Acta
Main Authors: Hu, Yang, Yu, Pei, Yu, Xinbo, Hu, Xingxue, Kawai, Toshihisa, Han, Xiaozhe
Format: Artigo
Sprog:Inglês
Udgivet: 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5567687/
https://ncbi.nlm.nih.gov/pubmed/28583714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2017.06.001
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