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Integration of the tricarboxylic acid (TCA) cycle with cAMP signaling and Sfl2 pathways in the regulation of CO(2) sensing and hyphal development in Candida albicans

Morphological transitions and metabolic regulation are critical for the human fungal pathogen Candida albicans to adapt to the changing host environment. In this study, we generated a library of central metabolic pathway mutants in the tricarboxylic acid (TCA) cycle, and investigated the functional...

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Библиографические подробности
Опубликовано в: :PLoS Genet
Главные авторы: Tao, Li, Zhang, Yulong, Fan, Shuru, Nobile, Clarissa J., Guan, Guobo, Huang, Guanghua
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2017
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5567665/
https://ncbi.nlm.nih.gov/pubmed/28787458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1006949
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