Integration of the tricarboxylic acid (TCA) cycle with cAMP signaling and Sfl2 pathways in the regulation of CO(2) sensing and hyphal development in Candida albicans

Morphological transitions and metabolic regulation are critical for the human fungal pathogen Candida albicans to adapt to the changing host environment. In this study, we generated a library of central metabolic pathway mutants in the tricarboxylic acid (TCA) cycle, and investigated the functional...

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Udgivet i:PLoS Genet
Main Authors: Tao, Li, Zhang, Yulong, Fan, Shuru, Nobile, Clarissa J., Guan, Guobo, Huang, Guanghua
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2017
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5567665/
https://ncbi.nlm.nih.gov/pubmed/28787458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1006949
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