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Electrostatic Interactions at the Dimer Interface Stabilize the E. coli β Sliding Clamp

Sliding clamps are ring-shaped oligomeric proteins that encircle DNA and associate with DNA polymerases for processive DNA replication. The dimeric Escherichia coli β-clamp is closed in solution but must adopt an open conformation to be assembled onto DNA by a clamp loader. To determine what factors...

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Bibliografische gegevens
Gepubliceerd in:Biophys J
Hoofdauteurs: Purohit, Anirban, England, Jennifer K., Douma, Lauren G., Tondnevis, Farzaneh, Bloom, Linda B., Levitus, Marcia
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The Biophysical Society 2017
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5567426/
https://ncbi.nlm.nih.gov/pubmed/28834716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2017.06.057
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