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Mutant p53 stimulates cell invasion through an interaction with Rad21 in human ovarian cancer cells

Missense mutations of TP53 are extremely common, and mutant p53 accumulation and gain-of-function play crucial roles in human ovarian cancer. Here, we investigated the role of mutant p53 in cell migration and invasion as well as its underlying molecular mechanisms in human ovarian cancer cells. Over...

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Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Ahn, Ji-Hye, Kim, Tae Jin, Lee, Jae Ho, Choi, Jung-Hye
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5567302/
https://ncbi.nlm.nih.gov/pubmed/28831167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-08880-4
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