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Analysis of mononucleotides by tandem mass spectrometry: investigation of fragmentation pathways for phosphate- and ribose-modified nucleotide analogues

Synthetic nucleotide and nucleic acid analogues are useful research tools and modern therapeutics. Hence, methods for the rapid and unambiguous identification of mononucleotides derived from organic syntheses or biological materials are of broad interest. Here, we analysed over 150 mononucleotides (...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Strzelecka, Dominika, Chmielinski, Sebastian, Bednarek, Sylwia, Jemielity, Jacek, Kowalska, Joanna
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5567097/
https://ncbi.nlm.nih.gov/pubmed/28827558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-09416-6
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