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Low TIM3 expression indicates poor prognosis of metastatic prostate cancer and acts as an independent predictor of castration resistant status

T cell immunoglobulin 3 (TIM3) is a cell surface star molecule expressed on T cells, and also marks dysfunctional CD8(+) T cells in various kinds of cancers. However, there are few studies focusing on the expression of TIM3 in tumor cells. In our study, we recruited 139 patients with metastatic pros...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Wu, Junlong, Lin, Guowen, Zhu, Yao, Zhang, Hailiang, Shi, Guohai, Shen, Yijun, Zhu, Yiping, Dai, Bo, Ye, Dingwei
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5567055/
https://ncbi.nlm.nih.gov/pubmed/28827755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-09484-8
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