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The purified yeast pre-mRNA splicing factor PRP2 is an RNA-dependent NTPase.

Unlike autocatalyzed self-splicing reactions, nuclear pre-mRNA splicing requires transacting macromolecules and ATP. A protein encoded by the PRP2 gene of Saccharomyces cerevisiae is required, in conjunction with ATP, for the first cleavage-ligation reaction of pre-mRNA splicing. In this study, we h...

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Udgivet i:EMBO J
Principais autores: Kim, S H, Smith, J, Claude, A, Lin, R J
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 1992
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC556699/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1534753/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1992.tb05291.x
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