Palmitoylation alters protein activity: blockade of G(o) stimulation by GAP-43.

The addition of palmitate to cysteine residues enhances the hydrophobicity of proteins, and consequently their membrane association. Here we have investigated whether this type of fatty acylation also regulates protein-protein interactions. GAP-43 is a neuronal protein that increases guanine nucleot...

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Библиографические подробности
Главные авторы: Sudo, Y, Valenzuela, D, Beck-Sickinger, A G, Fishman, M C, Strittmatter, S M
Формат: Artigo
Язык:Inglês
Опубликовано: 1992
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC556676/
https://ncbi.nlm.nih.gov/pubmed/1534749
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