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The Chronic Stages of Bovine Fasciola hepatica Are Dominated by CD4 T-Cell Exhaustion
Fasciola hepatica infection of ruminants leads to non-resolving chronic infection, as patency develops, there is switching to a TGF-β and IL-10 led response. Here, we explore the responses of CD4 T-cells within the major draining lymph nodes. We found minimal expression of Foxp3 within CD4 cells but...
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| Publicado no: | Front Immunol |
|---|---|
| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5566560/ https://ncbi.nlm.nih.gov/pubmed/28871261 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.01002 |
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