Sensitive genotyping of mutations in the EGFR gene from NSCLC patients using PCR-GoldMag lateral flow device

Epidermal growth factor receptor (EGFR) mutations predict better outcomes with EGFR tyrosine kinase inhibitors in patients with non-small cell lung cancer (NSCLC). Most common activating mutations include in-frame deletion in exon 19 and L858R substitution in exon 21, which account for >90% of al...

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Udgivet i:Sci Rep
Main Authors: Li, Xian-Ying, Zhang, Chao, Zhang, Qin-Lu, Zhu, Juan-Li, Liu, Qian, Chen, Ming-Wei, Yang, Xue-Min, Hui, Wen-Li, Cui, Ya-Li
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5566435/
https://ncbi.nlm.nih.gov/pubmed/28827701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-08210-8
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