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Analyses in zebrafish embryos reveal that nanotoxicity profiles are dependent on surface-functionalization controlled penetrance of biological membranes

Mesoporous silica nanoparticles (MSNs) are extensively explored as drug delivery systems, but in depth understanding of design-toxicity relationships is still scarce. We used zebrafish (Danio rerio) embryos to study toxicity profiles of differently surface functionalized MSNs. Embryos with the chori...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Paatero, Ilkka, Casals, Eudald, Niemi, Rasmus, Özliseli, Ezgi, Rosenholm, Jessica M., Sahlgren, Cecilia
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5566213/
https://ncbi.nlm.nih.gov/pubmed/28827674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-09312-z
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