Penicillin binding protein 2 is dispensable in Escherichia coli when ppGpp synthesis is induced.

Mecillinam, a beta-lactam antibiotic which specifically inactivates penicillin binding protein 2 (PBP2) in Escherichia coli, prevents lateral cell wall elongation, inducing spherical morphology and cell death. Two mecillinam resistant mutants, lov-1 and lovB, both able to dispense entirely with PBP2...

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Detalhes bibliográficos

Publicado no:	EMBO J
Principais autores:	Vinella, D, D'Ari, R, Jaffé, A, Bouloc, P
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Publishing Group 1992
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC556598/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1563353/ https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1992.tb05194.x
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