Two Distinct Mechanisms Govern RpoS-Mediated Repression of Tick-Phase Genes during Mammalian Host Adaptation by Borrelia burgdorferi, the Lyme Disease Spirochete

The alternative sigma factor RpoS plays a key role modulating gene expression in Borrelia burgdorferi, the Lyme disease spirochete, by transcribing mammalian host-phase genes and repressing σ(70)-dependent genes required within the arthropod vector. To identify cis regulatory elements involved in Rp...

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Veröffentlicht in:mBio
Hauptverfasser: Grove, Arianna P., Liveris, Dionysios, Iyer, Radha, Petzke, Mary, Rudman, Joseph, Caimano, Melissa J., Radolf, Justin D., Schwartz, Ira
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2017
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5565969/
https://ncbi.nlm.nih.gov/pubmed/28830947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01204-17
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