Chargement en cours...
Creation of a Novel Humanized Dystrophic Mouse Model of Duchenne Muscular Dystrophy and Application of a CRISPR/Cas9 Gene Editing Therapy
Duchenne muscular dystrophy is caused by mutations in DMD which disrupt the reading frame. Therapeutic strategies that restore DMD’s reading frame, such as exon skipping and CRISPR/Cas9, need to be tested in the context of the human DMD sequence in vivo. We have developed a novel dystrophic mouse mo...
Enregistré dans:
| Publié dans: | J Neuromuscul Dis |
|---|---|
| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2017
|
| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5565771/ https://ncbi.nlm.nih.gov/pubmed/28505980 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JND-170218 |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|