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Emerging role of DUBs in tumor metastasis and apoptosis: Therapeutic implication

Malfunction of ubiquitin-proteasome system is tightly linked to tumor formation and tumor metastasis. Targeting the ubiquitin-pathway provides a new strategy for anti-cancer therapy. Despite the parts played by ubiquitin modifiers, removal of ubiquitin from the functional proteins by the deubiquitin...

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Bibliographic Details
Published in:Pharmacol Ther
Main Authors: He, Mingjing, Zhou, Zhuan, Wu, George, Chen, Qianming, Wan, Yong
Format: Artigo
Language:Inglês
Published: 2017
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5565705/
https://ncbi.nlm.nih.gov/pubmed/28279784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pharmthera.2017.03.001
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