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miR-221 REGULATES CD44 IN HEPATOCELLULAR CARCINOMA THROUGH THE PI3K-AKT-mTOR PATHWAY

CD44 and miR-221 are upregulated in hepatocellular carcinoma (HCC) cell lines and tumors, however a connection between the two has not been identified. As the expression of miR-221 directly correlated with CD44 in HCC cells, we hypothesized that miR-221 may directly or indirectly regulate CD44 expre...

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Detalhes bibliográficos
Publicado no:Biochem Biophys Res Commun
Main Authors: Kim, Jihye, Jiang, Jinmai, Badawi, Mohamed, Schmittgen, Thomas D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5565483/
https://ncbi.nlm.nih.gov/pubmed/28442344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2017.04.121
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