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Toll-like receptor 4 deficiency alters nucleus accumbens synaptic physiology and drug reward behavior

Behavioral manifestations of drug-seeking behavior are causally linked to alterations of synaptic strength onto nucleus accumbens (NAc) medium spiny neurons (MSN). Although neuron-driven changes in physiology and behavior are well characterized, there is a lack of knowledge of the role of the immune...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Kashima, Daniel T., Grueter, Brad A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2017
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5565449/
https://ncbi.nlm.nih.gov/pubmed/28760987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1705974114
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