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Quantitative time-resolved chemoproteomics reveals that stable O-GlcNAc regulates box C/D snoRNP biogenesis

O-linked GlcNAcylation (O-GlcNAcylation), a ubiquitous posttranslational modification on intracellular proteins, is dynamically regulated in cells. To analyze the turnover dynamics of O-GlcNAcylated proteins, we developed a quantitative time-resolved O-linked GlcNAc proteomics (qTOP) strategy based...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Qin, Wei, Lv, Pinou, Fan, Xinqi, Quan, Baiyi, Zhu, Yuntao, Qin, Ke, Chen, Ying, Wang, Chu, Chen, Xing
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5565422/
https://ncbi.nlm.nih.gov/pubmed/28760965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1702688114
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