Binding of neurotrophin-3 to its neuronal receptors and interactions with nerve growth factor and brain-derived neurotrophic factor.

Neurotrophin-3 (NT-3) has low-affinity (Kd = 8 x 10(-10) M), as well as high-affinity receptors (Kd = 1.8 x 10(-11) M) on embryonic chick sensory neurons, the latter in surprisingly high numbers. Like the structurally related proteins nerve growth factor (NGF) and brain-derived neurotrophic factor (...

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Bibliographische Detailangaben
Veröffentlicht in:EMBO J
Hauptverfasser: Rodríguez-Tébar, A, Dechant, G, Götz, R, Barde, Y A
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 1992
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC556532/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1547788/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1992.tb05130.x
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