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Frequency of cholinergic and caudate nucleus dopaminergic deficits across pre-demented cognitive spectrum of Parkinson disease and evidence of interaction effects

IMPORTANCE: Little is known about the relative contributions of multisystem degenerative processes across the spectrum of pre-demented cognitive decline in Parkinson disease (PD). OBJECTIVE: To investigate the relative frequency of caudate nucleus dopaminergic and forebrain cholinergic deficits acro...

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Publicado en:JAMA Neurol
Autores principales: Bohnen, Nicolaas I., Albin, Roger L., Müller, Martijn L.T.M, Petrou, Myria, Kotagal, Vikas, Koeppe, Robert A, Scott, Peter J.H., Frey, Kirk A
Formato: Artigo
Lenguaje:Inglês
Publicado: 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5565160/
https://ncbi.nlm.nih.gov/pubmed/25506674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaneurol.2014.2757
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