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DNA polymerase II, the probable homolog of mammalian DNA polymerase epsilon, replicates chromosomal DNA in the yeast Saccharomyces cerevisiae.

Two temperature-sensitive DNA polymerase II mutants (pol2-9 and pol2-18) of the yeast Saccharomyces cerevisiae were isolated by the plasmid shuffling method. DNA polymerase II activity partially purified from both mutants was thermolabile, while DNA polymerase I and III activities remained thermotol...

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Dettagli Bibliografici
Pubblicato in:EMBO J
Autori principali: Araki, H, Ropp, P A, Johnson, A L, Johnston, L H, Morrison, A, Sugino, A
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 1992
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC556506/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1537345/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1992.tb05106.x
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