Immunoglobulin V gene replacement is caused by the intramolecular DNA deletion mechanism.

Circular DNA resulting from V gene replacement was studied with an A-MuLV transformed cell line containing ablts. This cell line undergoes V gene replacement at elevated temperatures in the immunoglobulin (Ig) heavy chain (H) gene. Examination of circular DNA revealed that a heptamer-related sequenc...

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Bibliografiske detaljer
Main Authors: Usuda, S, Takemori, T, Matsuoka, M, Shirasawa, T, Yoshida, K, Mori, A, Ishizaka, K, Sakano, H
Format: Artigo
Sprog:Inglês
Udgivet: 1992
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC556493/
https://ncbi.nlm.nih.gov/pubmed/1311252
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