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Enrichment and characterization of uncommitted B-cell precursors from fetal liver at day 12 of gestation.

We describe an assay system that allows precursor cells, uncommitted for heavy and light chain immunoglobulin expression, to develop into B lymphocytes that can differentiate to antibody-producing cells. Some precursors have the immunoglobulin loci in germ-line configuration. Approximately 200-1500...

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Detalhes bibliográficos
Main Authors: Cumano, A, Paige, C J
Formato: Artigo
Idioma:Inglês
Publicado em: 1992
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC556491/
https://ncbi.nlm.nih.gov/pubmed/1537338
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