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Niraparib in ovarian cancer: results to date and clinical potential
Ovarian cancer is the first cause of death from gynaecological malignancy. Germline mutation in BRCA1 and 2, two genes involved in the mechanisms of reparation of DNA damage, are showed to be related with the incidence of breast and ovarian cancer, both sporadic and familiar. PARP is a family of enz...
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| Publicado en: | Ther Adv Med Oncol |
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| Autores principales: | , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
SAGE Publications
2017
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5564880/ https://ncbi.nlm.nih.gov/pubmed/29081841 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1758834017718775 |
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