Niraparib in ovarian cancer: results to date and clinical potential

Ovarian cancer is the first cause of death from gynaecological malignancy. Germline mutation in BRCA1 and 2, two genes involved in the mechanisms of reparation of DNA damage, are showed to be related with the incidence of breast and ovarian cancer, both sporadic and familiar. PARP is a family of enz...

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Bibliographic Details
Published in:Ther Adv Med Oncol
Main Authors: Caruso, Davide, Papa, Anselmo, Tomao, Silverio, Vici, Patrizia, Panici, Pierluigi Benedetti, Tomao, Federica
Format: Artigo
Language:Inglês
Published: SAGE Publications 2017
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Reviews
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5564880/
https://ncbi.nlm.nih.gov/pubmed/29081841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1758834017718775
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