Next generation sequencing and molecular imaging identify EGFR mutation and amplification in a glioblastoma multiforme patient treated with an EGFR inhibitor: a case report

Epidermal growth factor receptor (EGFR) mutations and amplifications are frequently reported in glioblastoma multiforme (GBM) patients. In this case report, we utilize next-generation sequencing (NGS) and EGFR molecular imaging to investigate intratumoral heterogeneity in a male patient presenting w...

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Podrobná bibliografie
Vydáno v:Oncotarget
Hlavní autoři: Zhou, Ke, Yao, Hui, Zhang, Xuewen, Liu, Jiangang, Qi, Zhenyu, Xie, Xueshun, Xu, Xiaoting, Zhou, Youxin, Yu, Zhengquan, Wang, Zhong, Che, Yanjun, Huang, Yulun
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2017
Témata:
Case Report
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5564850/
https://ncbi.nlm.nih.gov/pubmed/28611289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.18148
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