Adverse genomic alterations and stemness features are induced by field cancerization in the microenvironment of hepatocellular carcinomas

Hepatocellular Carcinoma (HCC) commonly develops in chronically damaged liver tissues. The resulting regenerative and inflammatory processes create an adverse milieu that promotes tumor-initiation and progression. A better understanding of the hepatic tumor-microenvironment interaction might infer p...

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Vydáno v:Oncotarget
Hlavní autoři: Castven, Darko, Fischer, Michael, Becker, Diana, Heinrich, Stefan, Andersen, Jesper B., Strand, Dennis, Sprinzl, Martin F., Strand, Susanne, Czauderna, Carolin, Heilmann-Heimbach, Stefanie, Roessler, Stephanie, Weinmann, Arndt, Wörns, Marcus A., Thorgeirsson, Snorri S., Galle, Peter R., Matter, Matthias S., Lang, Hauke, Marquardt, Jens U.
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2017
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5564717/
https://ncbi.nlm.nih.gov/pubmed/28415775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.16231
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