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A Syngeneic Mouse Model of Metastatic Renal Cell Carcinoma for Quantitative and Longitudinal Assessment of Preclinical Therapies

Renal cell carcinoma (RCC) affects > 60,000 people in the United States annually, and ~ 30% of RCC patients have multiple metastases at the time of diagnosis. Metastatic RCC (mRCC) is incurable, with a median survival time of only 18 months. Immune-based interventions (e.g., interferon (IFN) and...

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Detalhes bibliográficos
Publicado no:J Vis Exp
Main Authors: Murphy, Katherine A., James, Britnie R., Wilber, Andrew, Griffith, Thomas S.
Formato: Artigo
Idioma:Inglês
Publicado em: MyJove Corporation 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5564692/
https://ncbi.nlm.nih.gov/pubmed/28448047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/55080
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