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Distamycin-induced inhibition of homeodomain-DNA complexes.

The mobility shift assay was used to study the competition of the minor groove binder distamycin A with either an Antennapedia homeodomain (Antp HD) peptide or derivatives of a fushi tarazu homeodomain (ftz HD) peptide for their AT-rich DNA binding site. The results show that distamycin and the home...

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Bibliographic Details
Published in:EMBO J
Main Authors: Dorn, A, Affolter, M, Müller, M, Gehring, W J, Leupin, W
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 1992
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC556448/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1346762/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1992.tb05050.x
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