Critical role of a common transcription factor, IRF-1, in the regulation of IFN-beta and IFN-inducible genes.

Interferon regulatory factor 1 (IRF-1) is a protein that binds to cis-elements within the promoter of interferon (IFN)-beta and some IFN-inducible genes. We used a human fibroblast line, GM-637, to generate stable transfectants constitutively expressing IRF-1 mRNA in either the sense or antisense or...

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主要な著者: Reis, L F, Harada, H, Wolchok, J D, Taniguchi, T, Vilcek, J
フォーマット: Artigo
言語:Inglês
出版事項: 1992
主題:
Research Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC556439/
https://ncbi.nlm.nih.gov/pubmed/1371248
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