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High PKC α and Low E-Cadherin Expression Contribute to High Migratory Activity of Colon Carcinoma Cells

The protein kinase C (PKC) is a family of serine/threonine kinases that are key regulatory enzymes involved in growth, differentiation, cytoskeletal reorganization, tumor promotion, and migration. We investigated the functional involvement of PKC isotypes and of E-cadherin in the regulation of the l...

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Detalhes bibliográficos
Main Authors: Masur, Kai, Lang, Kerstin, Niggemann, Bernd, Zanker, Kurt S., Entschladen, Frank
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC55643/
https://ncbi.nlm.nih.gov/pubmed/11451996
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