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Pregnancy-Induced Changes in the Pharmacokinetics of Caffeine and Its Metabolites

This study sought to assess the pharmacokinetic (PK) changes of caffeine and its CYP1A2 metabolites across the 3 trimesters of pregnancy. A prospective, multicenter PK study was conducted among 59 pregnant women (93.2% white) who were studied once during a trimester. One beverage with 30–95 mg caffe...

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Publicat a:J Clin Pharmacol
Autors principals: Yu, Tian, Campbell, Sarah C., Stockmann, Chris, Tak, Casey, Schoen, Katherine, Clark, Erin A. S., Varner, Michael W., Spigarelli, Michael G., Sherwin, Catherine M. T.
Format: Artigo
Idioma:Inglês
Publicat: 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5564294/
https://ncbi.nlm.nih.gov/pubmed/26358647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcph.632
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