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Topological and Mutational Analysis of Saccharomyces cerevisiae Ste14p, Founding Member of the Isoprenylcysteine Carboxyl Methyltransferase Family

Eukaryotic proteins that terminate in a CaaX motif undergo three processing events: isoprenylation, C-terminal proteolytic cleavage, and carboxyl methylation. In Saccharomyces cerevisiae, the latter step is mediated by Ste14p, an integral endoplasmic reticulum membrane protein. Ste14p is the foundin...

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Detalles Bibliográficos
Main Authors: Romano, Julia D., Michaelis, Susan
Formato: Artigo
Idioma:Inglês
Publicado: The American Society for Cell Biology 2001
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC55642/
https://ncbi.nlm.nih.gov/pubmed/11451995
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