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Chromatographic Characterization and Method Development for Determination of Levetiracetam in Saliva: Application to Correlation with Plasma Levels

Levetiracetam (LVT) is a widely used antiepileptic drug (AED). A less invasive sampling method for therapeutic drug monitoring (TDM) would be very useful particularly for children. Saliva has been shown as an adequate sample for TDM of some AEDs. Due to the high hydrophilicity of LVT its separation...

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Detalhes bibliográficos
Publicado no:J Anal Methods Chem
Main Authors: Hamdan, Imad I., Alsous, Mervat, Masri, Amira Taher
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5564075/
https://ncbi.nlm.nih.gov/pubmed/28848686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/7846742
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