The dependence receptor UNC5H2 mediates apoptosis through DAP-kinase

Netrin-1 receptors UNC5H (UNC5H1–4) were originally proposed to mediate the chemorepulsive activity of netrin-1 during axonal guidance processes. However, UNC5H receptors were more recently described as dependence receptors and, as such, able to trigger apoptosis in the absence of netrin-1. They wer...

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Bibliografiske detaljer
Main Authors: Llambi, Fabien, Lourenço, Filipe Calheiros, Gozuacik, Devrim, Guix, Catherine, Pays, Laurent, Del Rio, Gabriel, Kimchi, Adi, Mehlen, Patrick
Format: Artigo
Sprog:Inglês
Udgivet: 2005
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC556396/
https://ncbi.nlm.nih.gov/pubmed/15729359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600584
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